Population genomics of the endangered giant Galápagos tortoise. (Registro nro. 13061)

Detalles MARC
000 -LEADER
fixed length control field 02511nab a22003257a 4500
003 - CONTROL NUMBER IDENTIFIER
control field EC-PaCDF
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20171204141423.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170725t20132013xxu|||||||||||||||||eng||
040 ## - CATALOGING SOURCE
Original cataloging agency EC-PaCDF
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Edition number 21
Classification number 597.9246
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Loire, Etienne.
245 10 - TITLE STATEMENT
Title Population genomics of the endangered giant Galápagos tortoise.
520 0# - SUMMARY, ETC.
Summary, etc. Background: The giant Galápagos tortoise, Chelonoidis nigra, is a large-sized terrestrial chelonian of high patrimonial interest. The species recently colonized a small continental archipelago, the Galápagos Islands, where it has been facing novel environmental conditions and limited resource availability. To explore the genomic consequences of this ecological shift, we analyze the transcriptomic variability of five individuals of C. nigra,andcompareittosimilar data obtained from several continental species of turtles.<br/>Results: Having clarified the timing of divergence in the Chelonoidis genus,wereportinC. nigra averylowlevelof genetic polymorphism, signatures of a weakened efficacy of purifying selection, and an elevated mutation load in coding and regulatory sequences. These results are consistent with the hypothesis of an extremely low long-term effective population size in this insular species. Functional evolutionary analyses reveal a reduced diversity of immunity genes in C. nigra, in line with the hypothesis of attenuated pathogen diversity in islands, and an increased selective pressure on genes involved in response to stress, potentially related to the climatic instability of its environment and its elongated lifespan. Finally, we detect no population structure or homozygosity excess in our five-individual sample.<br/>Conclusions: These results enlighten the molecular evolution of an endangered taxon in a stressful environment and point to island endemic species as a promising model for the study of the deleterious effects on genome evolution of a reduced long-term population size.<br/>
546 ## - LANGUAGE NOTE
Language note English
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Giant tortoise.
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Tortugas Gigantes.
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Galapagos.
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Chelonoidis nigra.
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Endangered.
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Peligro de extinción.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Chiari, Ylenia.
9 (RLIN) 2256
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bernard, Aurélien.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Cahais, Vincent.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Romiguier, Jonathan.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lourenço, Joao Miguel.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Galtier, Nicolas.
773 0# - HOST ITEM ENTRY
Related parts Vol. 14 (2013), p. 1-11
Title Genome Biology.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Koha item type Artículo
Existencias
Withdrawn status Source of classification or shelving scheme Damaged status Not for loan Collection code Home library Current library Shelving location Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
  Dewey Decimal Classification     Galápagos Corley Smith Library Corley Smith Library Artículos 25/07/2017   597.9246 LOI 2017-2146 25/07/2017 25/07/2017 Artículo
  Dewey Decimal Classification     Galápagos Corley Smith Library Corley Smith Library Colección PDF 25/07/2017   597.9246 LOI 2013 2021-1831 25/07/2017 25/07/2017 Documento electrónico

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Digital